This video provides approximately 15-minute didactic overview of the barriers to clozapine use and tips for implementation of clozapine with a focus on making sure the participants learn how to list the most common barriers to clozapine use, understand barriers that can be best overcome to improve clozapine use, describe how using a team-based approach can facilitate clozapine use. This is followed by a discussion on the topic between the presenter, other experts and providers.
Session 12: Clozapine and Myocarditis, Cardiomyopathy and Fever: Potential Mechanisms, Risk mitigation, Monitoring and Rechallenge of These Side Effects (48 minutes)
This video provides an approximately 15-minute didactic overview of clozapine and myocarditis, cardiomyopathy, and fever. Potential mechanisms, risk mitigation, monitoring and rechallenge of these side effects with a focus on making sure the participants learn how to describe the prevalence of cardiac-related adverse events with clozapine, list risk factors and symptoms of myocarditis and cardiomyopathy during clozapine treatment, outline monitoring parameters for myocarditis and cardiomyopathy in clozapine-treated patients and strategies for prevention, discuss the potential for rechallenge in patients who have recovered from clozapine-associated myocarditis or cardiomyopathy. This is followed by a discussion on the topic between the presenter, other experts and providers.
Session 13: Clozapine and Seizures; Reducing Risk, Monitoring and Management (32 minutes)
This video provides approximately 15-minute didactic overview of clozapine and seizures; reducing risk, monitoring and management with a focus on making sure the participants learn how to understand the seizure risk and black box warnings associated with clozapine, describe the risk and benefits and the role of dose in seizure risk and prevention, and identify evidence-based seizure management strategies and the role of prophylactic treatment. This is followed by a discussion on the topic between the presenter, other experts and providers.
Session 14: Weight and Metabolic Management of Clozapine (45 minutes)
This video provides approximately 15-minute didactic overview of weight and metabolic management of clozapine with a focus on making sure the participants learn how to describe the risks of weight gain and metabolic changes with clozapine, discuss monitoring parameters for weight gain and metabolic parameter during clozapine treatment, list the nonpharmacological and pharmacological interventions for prevention of weight gain, address treatment strategies for weight loss in overweight/obese patients. This is followed by a discussion on the topic between the presenter, other experts and providers.